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Saturday, 10 March 2012

Jalyn

Generic Name: dutasteride and tamsulosin (doo TAS ter ide and tam soo LOE sin)

Brand Names: Jalyn

What is dutasteride and tamsulosin?

Dutasteride prevents the conversion of testosterone to dihydrotestosterone (DHT) in the body. DHT is involved in the development of benign prostatic hyperplasia (BPH).

Tamsulosin is in a group of drugs called alpha-adrenergic (AL-fa ad-ren-ER-jik) blockers. Tamsulosin relaxes the muscles in the prostate and bladder neck, making it easier to urinate.

The combination of dutasteride and tamsulosin is used to treat benign prostatic hyperplasia (BPH) in men with an enlarged prostate.

Dutasteride and tamsulosin may also be used for purposes not listed in this medication guide.

What is the most important information I should know about dutasteride and tamsulosin?

You should not use this medication if you are allergic to dutasteride (Avodart) or tamsulosin (Flomax). Do not take dutasteride and tamsulosin if you are also taking alfuzosin (Uroxatral), doxazosin (Cardura), prazosin (Minipress), silodosin (Rapaflo), tamsulosin (Flomax), or terazosin (Hytrin). Dutasteride and tamsulosin should never be taken by a woman, a child, or a teenager. Dutasteride can be absorbed through the skin, and women or children should not be permitted to handle dutasteride and tamsulosin capsules. This medication can cause birth defects if a woman is exposed to it during pregnancy. Dutasteride and tamsulosin capsules should not be handled by a woman who is pregnant or who may become pregnant. If a woman accidentally comes into contact with this medication from a leaking capsule, wash the area with soap and water right away. Do not donate blood while taking this medication and for at least 6 months after your treatment ends. Dutasteride can be carried in the blood and could cause birth defects if a pregnant women receives a transfusion with blood that contains dutasteride. Using dutasteride and tamsulosin may increase your risk of developing prostate cancer. Your doctor will perform tests to make sure you do not have other conditions that would prevent you from safely using dutasteride and tamsulosin.

Tamsulosin can affect your pupils during cataract surgery. Tell your eye surgeon ahead of time that you are using this medication. Do not stop using dutasteride and tamsulosin before surgery unless your surgeon tells you to.

There are many other drugs that can interact with dutasteride and tamsulosin. Tell your doctor about all medications you use.

What should I discuss with my healthcare provider before taking dutasteride and tamsulosin?

To make sure you can safely take this medication, tell your doctor if you have any of these other conditions:

low blood pressure;

high blood pressure (hypertension);

liver disease;

severe kidney disease;

a history of prostate cancer; or

if you are allergic to sulfa drugs or to finasteride (Propecia, Proscar).

Using dutasteride and tamsulosin may increase your risk of developing prostate cancer. Your doctor will perform tests to make sure you do not have other conditions that would prevent you from safely using dutasteride and tamsulosin. Although dutasteride and tamsulosin is not for use by women, this medication can cause birth defects if a woman is exposed to it during pregnancy. Dutasteride and tamsulosin capsules should not be handled by a woman who is pregnant or who may become pregnant. If a woman accidentally comes into contact with this medication from a leaking capsule, wash the area with soap and water right away.

How should I take dutasteride and tamsulosin?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Dutasteride and tamsulosin is usually taken once a day, approximately 30 minutes after a meal. Try to take this medication at the same time each day. Do not crush, chew, or open a dutasteride and tamsulosin capsule. Swallow it whole. A broken or leaking dutasteride and tamsulosin capsule can irritate your lips, mouth, or throat. Tamsulosin lowers blood pressure and may cause dizziness or fainting, especially when you first start taking dutasteride and tamsulosin. Call your doctor if you have severe dizziness or feel like you might pass out. It may take up to 6 months before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve.

To be sure this medication is helping your condition and not causing harmful effects, your blood may need to be tested often. Your doctor will also test your prostate specific antigen (PSA) to check for prostate cancer. Visit your doctor regularly.

Store at room temperature away from moisture and heat. Do not use a capsule that has been exposed to high heat, which can cause the capsule to change shape or color.

See also: Jalyn dosage (in more detail)

What happens if I miss a dose?

Take the missed dose 30 minutes after your next meal. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

If you miss your doses for several days in a row, contact your doctor before restarting the medication. You may need a lower dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include extreme dizziness or fainting.

What should I avoid while taking dutasteride and tamsulosin?

Do not donate blood while taking this medication and for at least 6 months after your treatment ends. Dutasteride can be carried in the blood and could cause birth defects if a pregnant women receives a transfusion with blood that contains dutasteride. Dutasteride and tamsulosin may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

Dutasteride and tamsulosin side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop taking this medication and call your doctor at once if you have a serious side effect such as:

feeling like you might pass out; or

penis erection that is painful or lasts 4 hours or longer.

Less serious side effects may include:

decreased libido (sex drive);

decreased amount of semen released during sex;

impotence (trouble getting or keeping an erection);

breast tenderness or enlargement;

mild dizziness; or

runny nose.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect dutasteride and tamsulosin?

Tell your doctor about all other medications you use, especially:

cimetidine (Tagamet);

conivaptan (Vaprisol);

cyclosporine (Gengraf, Neoral, Sandimmune);

imatinib (Gleevec);

isoniazid (for treating tuberculosis);

methimazole (Tapazole);

pioglitazone (Actos);

ropinirole (Requip);

ticlopidine (Ticlid);

a blood thinner such as warfarin (Coumadin, Jantoven);

an antibiotic such as clarithromycin (Biaxin), doxycycline (Adoxa, Alodox, Avidoxy, Oraxyl, Doryx, Oracea, Vibramycin), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin, Pediazole), metronidazole (Flagyl, Protostat), telithromycin (Ketek), terbinafine (Lamisil), or tetracycline (Ala-Tet, Brodspec, Panmycin, Sumycin, Tetracap);

an antidepressant such as clomipramine (Anafranil), desipramine (Norpramin), duloxetine (Cymbalta), fluoxetine (Prozac, Sarafem), nefazodone, paroxetine (Paxil), sertraline (Zoloft), tranylcypromine (Parnate), or trazodone (Desyrel, Oleptro);

antifungal medication such as fluconazole (Diflucan), itraconazole (Sporanox), ketoconazole (Nizoral), miconazole (Oravig), or voriconazole (Vfend);

anti-malaria medication such as chloroquine (Arelan) or pyrimethamine (Daraprim), or quinine (Qualaquin);

erectile dysfunction medicine such as sildenafil (Viagra), tadalafil (Cialis), or vardenafil (Levitra);

heart or blood pressure medication such as amiodarone (Cordarone, Pacerone), nicardipine (Cardene), or quinidine (Quin-G), and others;

HIV/AIDS medicine such as atazanavir (Reyataz), delavirdine (Rescriptor), efavirenz (Sustiva), fosamprenavir (Lexiva), indinavir (Crixivan), nelfinavir (Viracept), saquinavir (Invirase), or ritonavir (Norvir); or

medicine to treat psychiatric disorders, such as aripiprazole (Abilify), chlorpromazine (Thorazine), clozapine (Clozaril, FazaClo), fluphenazine (Permitil, Prolixin), haloperidol (Haldol), perphenazine (Trilafon), or thioridazine (Mellaril).

This list is not complete and there are many other drugs that can interact with dutasteride and tamsulosin. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.

More Jalyn resources

Jalyn Side Effects (in more detail)
Jalyn Dosage
Jalyn Use in Pregnancy & Breastfeeding
Jalyn Drug Interactions
Jalyn Support Group
11 Reviews for Jalyn - Add your own review/rating

Jalyn Prescribing Information (FDA)

Jalyn Advanced Consumer (Micromedex) - Includes Dosage Information

Jalyn MedFacts Consumer Leaflet (Wolters Kluwer)

Jalyn Consumer Overview

Compare Jalyn with other medications

Benign Prostatic Hyperplasia

Where can I get more information?

Your pharmacist can provide more information about dutasteride and tamsulosin.

See also: Jalyn side effects (in more detail)

Friday, 9 March 2012

nepafenac ophthalmic

Generic Name: nepafenac ophthalmic (ne PA fan ak off THAL mik)

Brand Names: Nevanac

What is nepafenac ophthalmic?

Nepafenac is in a group of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). It reduces pain and inflammation in the eyes.

Nepafenac ophthalmic (for the eyes) is used to reduce pain and swelling after cataract surgery.

Nepafenac ophthalmic may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about nepafenac ophthalmic?

Before using nepafenac ophthalmic, tell your doctor if you are allergic to any drugs or other eye drops

Also tell your doctor if you have diabetes, dry eye syndrome, rheumatoid arthritis, a bleeding or blood-clotting disorder, such as hemophilia, or arthritis.

Do not use this medication while you are wearing contact lenses. This medication may contain a preservative that can be absorbed by soft contact lenses. Wait at least 15 minutes after using nepafenac before putting your contact lenses in. Do not allow the dropper tip to touch any surface, including the eyes or hands. If the dropper becomes contaminated it could cause an infection in your eye, which can lead to vision loss or serious damage to the eye. Do not use nepafenac ophthalmic for longer than 14 days after your surgery unless your doctor tells you to.

What should I discuss with my healthcare professional before using nepafenac ophthalmic?

You should not use this medication if you are allergic to nepafenac.

If you have any of these other conditions, you may need a dose adjustment or special tests to safely use this medication:

diabetes;

dry eye syndrome;

rheumatoid arthritis;

a bleeding or blood-clotting disorder, such as hemophilia; or

arthritis.

Do not use nepafenac ophthalmic while wearing contact lenses. If you wear contact lenses take them out or talk to your doctor before using the medication.

FDA pregnancy category C. This medication may be harmful to an unborn baby, especially if during the last part of pregnancy. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether nepafenac ophthalmic passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I use nepafenac ophthalmic?

Use this medication exactly as prescribed by your doctor. Do not use it in larger amounts or for longer than recommended. Follow the directions on your prescription label.

Nepafenac is usually given as 1 drop in the affected eye 3 times per day, starting 1 day before cataract surgery.

Do not use nepafenac ophthalmic for longer than 14 days after your surgery unless your doctor tells you to. Wash your hands before using the eye drops. Do not use this medication while you are wearing contact lenses. This medication may contain a preservative that can be absorbed by soft contact lenses. Wait at least 15 minutes after using nepafenac before putting your contact lenses in. Shake the eye drops well just before you use them.

To apply the eye drops:

Tilt your head back slightly and pull down your lower eyelid to create a small pocket. Hold the dropper above the eye with the dropper tip down. Look up and away from the dropper as you squeeze out a drop, then close your eye.

Gently press your finger to the inside corner of the eye (near your nose) for about 1 minute to keep the liquid from draining into your tear duct. If you use more than one drop in the same eye, wait about 5 minutes before putting in the next drop.

Do not allow the dropper tip to touch any surface, including the eyes or hands. If the dropper becomes contaminated it could cause an infection in your eye, which can lead to vision loss or serious damage to the eye.

Do not use the eye drops if the liquid has changed colors or has particles in it. Call your doctor for a new prescription.

Keep using any other eye drops your doctor has prescribed, including drops to treat glaucoma. Use only the eye medications your doctor has prescribed.

Store the drops at room temperature away from heat and moisture. Keep the bottle tightly closed when not in use.

What happens if I miss a dose?

Use the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

An overdose of nepafenac ophthalmic is not likely to cause life-threatening symptoms.

What should I avoid while using nepafenac ophthalmic?

Do not touch the dropper to any surface, including your eyes or hands. The dropper is sterile. If it becomes contaminated, it could cause an infection in your eye. Do not use any other eye medications that have not been prescribed or recommended by your doctor.

Do not use nepafenac ophthalmic while wearing contact lenses. If you wear contact lenses take them out or talk to your doctor before using the medication.

Nepafenac ophthalmic side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have vision problems, crusting or drainage of your eyes, swollen eyelids, or severe eye pain.

Less serious side effects may be more likely to occur (some are effects of cataract surgery and not side effects of the medication):

dry or sticky feeling in the eye;

feeling like something is in your eye;

eye redness;

itching or watering of the eye;

increased sensitivity to light;

headache;

nausea, vomiting; or

stuffy nose.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Nepafenac ophthalmic Dosing Information

Usual Adult Dose for Postoperative Increased Intraocular Pressure:

One drop instilled in the affected eye(s) three times a day beginning 1 day prior to surgery, on the day of surgery, and for 14 days following surgery.

Usual Pediatric Dose for Postoperative Ocular Inflammation:

>= 10 years:
One drop instilled in the affected eye(s) three times a day beginning 1 day prior to surgery, on the day of surgery, and for 14 days following surgery.

What other drugs will affect nepafenac ophthalmic?

Before using this medication, tell your doctor if you also use any steroid medication, including steroids eye drops.

This list is not complete and there may be other drugs that can interact with nepafenac ophthalmic. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

More nepafenac ophthalmic resources

Nepafenac ophthalmic Side Effects (in more detail)
Nepafenac ophthalmic Dosage
Nepafenac ophthalmic Use in Pregnancy & Breastfeeding
Nepafenac ophthalmic Drug Interactions
Nepafenac ophthalmic Support Group
1 Review for Nepafenac - Add your own review/rating

Nevanac Prescribing Information (FDA)

Nevanac Monograph (AHFS DI)

Nevanac Advanced Consumer (Micromedex) - Includes Dosage Information

Nevanac MedFacts Consumer Leaflet (Wolters Kluwer)

Nevanac Consumer Overview

Compare nepafenac ophthalmic with other medications

Postoperative Increased Intraocular Pressure
Postoperative Ocular Inflammation

Where can I get more information?

Your doctor or pharmacist can provide more information about nepafenac ophthalmic.

See also: nepafenac side effects (in more detail)

Tuesday, 6 March 2012

Sular Extended-Release Tablets

Pronunciation: nye-SOL-di-peen
Generic Name: Nisoldipine
Brand Name: Sular

Sular Extended-Release Tablets are used for:

Treating high blood pressure. It may be used alone on in combination with other high blood pressure medicines. It may also be used for other conditions as determined by your doctor.

Sular Extended-Release Tablets are a calcium channel blocker. It works by dilating (widening) the arteries.

Do NOT use Sular Extended-Release Tablets if:

you are allergic to any ingredient in Sular Extended-Release Tablets or to other dihydropyridines (eg, amlodipine)

you are taking phenytoin

Contact your doctor or health care provider right away if any of these apply to you.

Before using Sular Extended-Release Tablets:

Some medical conditions may interact with Sular Extended-Release Tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding

if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

if you have allergies to medicines, foods, or other substances

if you are allergic to salicylates (eg, aspirin)

if you have chest pain, heart blood vessel disease, heart problems (eg, heart failure, ventricle problems), liver problems (eg, cirrhosis), or a history of low blood pressure

Some MEDICINES MAY INTERACT with Sular Extended-Release Tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:

Cimetidine or HIV protease inhibitors (eg, ritonavir) because they may increase the risk of Sular Extended-Release Tablets's side effects

Phenytoin because it may decrease Sular Extended-Release Tablets's effectiveness

This may not be a complete list of all interactions that may occur. Ask your health care provider if Sular Extended-Release Tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Sular Extended-Release Tablets:

Use Sular Extended-Release Tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Take Sular Extended-Release Tablets by mouth on an empty stomach at least 1 hour before or 2 hours after eating.

Swallow Sular Extended-Release Tablets whole. Do not break, crush, or chew before swallowing.

Do not eat grapefruit or drink grapefruit juice while you use Sular Extended-Release Tablets.

Taking Sular Extended-Release Tablets at the same time each day will help you remember to take it.

If you miss a dose of Sular Extended-Release Tablets, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Sular Extended-Release Tablets.

Important safety information:

Sular Extended-Release Tablets may cause dizziness, drowsiness, or lightheadedness. These effects may be worse if you take it with alcohol or certain medicines. Use Sular Extended-Release Tablets with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

Patients who take medicine for high blood pressure often feel tired or run down for a few weeks after starting treatment. Be sure to take your medicine even if you may not feel "normal." Tell your doctor if you develop any new symptoms.

Sular Extended-Release Tablets may contain tartrazine dye (FD&C Yellow No. 5). This may cause an allergic reaction in some patients. If you have ever had an allergic reaction to tartrazine, ask your pharmacist if your product has tartrazine in it.

Lab tests, including blood pressure checks, may be performed while you use Sular Extended-Release Tablets. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

Use Sular Extended-Release Tablets with caution in the ELDERLY; they may be more sensitive to its effects.

Sular Extended-Release Tablets should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.

PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Sular Extended-Release Tablets while you are pregnant. It is not known if Sular Extended-Release Tablets are found in breast milk. Do not breast-feed while taking Sular Extended-Release Tablets.

If you stop taking Sular Extended-Release Tablets suddenly, you may have WITHDRAWAL symptoms. These may include chest pain.

Possible side effects of Sular Extended-Release Tablets:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; flushing; headache; lightheadedness; mild swelling of the arms, legs, feet, or hands.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; fainting; fast or irregular heartbeat; fever, chills, or persistent sore throat; loss of vision or other vision changes; mood or mental changes; severe or persistent dizziness or headache; severe or persistent swelling of the arms, legs, feet, or hands; shortness of breath; sudden unusual weight gain; tender, bleeding, or swollen gums; unusual tiredness or weakness.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Sular side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include confusion; drowsiness; slowed or irregular heartbeat; slurred speech; weakness.

Proper storage of Sular Extended-Release Tablets:

Store Sular Extended-Release Tablets at room temperature, between 68 and 77 degrees F (20 and 25 degrees C), in a tightly closed container. Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Sular Extended-Release Tablets out of the reach of children and away from pets.

General information:

If you have any questions about Sular Extended-Release Tablets, please talk with your doctor, pharmacist, or other health care provider.

Sular Extended-Release Tablets are to be used only by the patient for whom it is prescribed. Do not share it with other people.

If your symptoms do not improve or if they become worse, check with your doctor.

Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Sular Extended-Release Tablets. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

More Sular resources

Sular Side Effects (in more detail)
Sular Dosage
Sular Use in Pregnancy & Breastfeeding
Drug Images
Sular Drug Interactions
Sular Support Group
1 Review for Sular - Add your own review/rating

Compare Sular with other medications

Angina Pectoris Prophylaxis
High Blood Pressure
Raynaud's Syndrome

Monday, 5 March 2012

Auditory Processing Disorder Medications

Definition of Auditory Processing Disorder: Auditory Processing Disorder (APD) is a disorder in the way auditory information is processed in the brain.

Drugs associated with Auditory Processing Disorder

The following drugs and medications are in some way related to, or used in the treatment of Auditory Processing Disorder. This service should be used as a supplement to, and NOT a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

Drug List:

Focalin

Focalin-Xr-Extended-Release-Capsules

Friday, 2 March 2012

ferrous sulfate and folic acid

Generic Name: ferrous sulfate and folic acid (FER us SUL fate and FOE lik AS id)

Brand Names: Slow Fe with Folic Acid

What is ferrous sulfate and folic acid?

Ferrous sulfate is a type of iron. You normally get iron from the foods you eat. In your body, iron becomes a part of your hemoglobin (HEEM o glo bin) and myoglobin (MY o glo bin). Hemoglobin carries oxygen through your blood to tissues and organs. Myoglobin helps your muscle cells store oxygen.

Folic acid helps your body produce and maintain new cells, and also helps prevent changes to DNA that may lead to cancer.

Ferrous sulfate and folic acid is used to treat iron deficiency anemia (a lack of red blood cells caused by having too little iron in the body).

Ferrous sulfate and folic acid may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about ferrous sulfate and folic acid?

Before using this medication, tell your doctor if you are allergic to any drugs, or if you have iron overload syndrome, hemolytic anemia (a lack of red blood cells), porphyria (a genetic enzyme disorder that causes symptoms affecting the skin or nervous system), thalassemia (a genetic disorder of red blood cells), if you are an alcoholic, or if you receive regular blood transfusions.

Seek emergency medical attention if you think you have used too much of this medicine, or if anyone has accidentally swallowed it. An overdose of iron can be fatal, especially in a young child.

Overdose symptoms may include nausea, severe stomach pain, bloody diarrhea, coughing up blood or vomit that looks like coffee grounds, shallow breathing, weak and rapid pulse, pale skin, blue lips, and seizure (convulsions).

Do not give ferrous sulfate to a child without the advice of a doctor. Take ferrous sulfate and folic acid on an empty stomach, at least 1 hour before or 2 hours after a meal. Avoid taking antacids or antibiotics within 2 hours before or after taking ferrous sulfate and folic acid.

Ferrous sulfate and folic acid is only part of a complete program of treatment that may also include a special diet. It is very important to follow the diet plan created for you by your doctor or nutrition counselor. You should become very familiar with the list of foods you should eat to make sure you get enough iron and folic acid from both your diet and your medication.

What should I discuss with my health care provider before taking ferrous sulfate and folic acid?

Before using this medication, tell your doctor if you are allergic to any drugs, or if you have:

iron overload syndrome;

hemolytic anemia (a lack of red blood cells);

porphyria (a genetic enzyme disorder that causes symptoms affecting the skin or nervous system);

thalassemia (a genetic disorder of red blood cells);

if you are an alcoholic; or

if you receive regular blood transfusions.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take ferrous sulfate and folic acid.

It is not known whether this medication could be harmful to an unborn baby. Tell your doctor if you become pregnant during treatment. It is not known whether ferrous sulfate and folic acid passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not give this medication to a child without the advice of a doctor.

How should I take ferrous sulfate and folic acid?

Use this medication exactly as directed on the label, or as prescribed by your doctor. Do not use it in larger amounts or for longer than recommended.

Take this medication on an empty stomach, at least 1 hour before or 2 hours after a meal. Avoid taking antacids or antibiotics within 2 hours before or after taking ferrous sulfate . Take this medication with a full glass of water. Do not crush, chew, break, or open the extended-release tablet. Swallow the pill whole. Breaking or opening the pill may cause too much of the drug to be released at one time.

Ferrous sulfate can stain your teeth, but this effect is temporary. To prevent tooth staining, mix the liquid form of ferrous sulfate with water or fruit juice (not with milk) and drink the mixture through a straw. You may also clean your teeth with baking soda once per week to treat any tooth staining.

Store this medicine at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine, or if anyone has accidentally swallowed it. An overdose of iron can be fatal, especially in a young child.

What should I avoid while taking ferrous sulfate and folic acid?

Do not take any vitamin or mineral supplements that your doctor has not prescribed or recommended.

Avoid taking an antibiotic medicine within 2 hours before or after you take ferrous sulfate and folic acid. This is especially important if you are taking an antibiotic such as ciprofloxacin (Cipro), doxycycline (Adoxa, Doryx, Oracea, Vibramycin), gatifloxacin (Tequin), levofloxacin (Levaquin), minocycline (Dynacin, Minocin, Solodyn, Vectrin), or sparfloxacin (Zagam).

Certain foods can also make it harder for your body to absorb this medication. Avoid taking this medication within 1 hour before or 2 hours after eating fish, meat, liver, and whole grain or "fortified" breads or cereals.

Avoid using antacids without your doctor's advice. Use only the specific type of antacid your doctor recommends. Antacids contain different medicines and some types can make it harder for your body to absorb ferrous sulfate.

Ferrous sulfate and folic acid side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have any of these serious side effects:

sore throat, trouble swallowing;

severe stomach pain; or

blood in your stools.

Less serious side effects may include:

diarrhea;

constipation;

nausea, vomiting, heartburn;

leg pain; or

darkened skin or urine color.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect ferrous sulfate and folic acid?

Before using ferrous sulfate and folic acid, tell your doctor if you are using any of the following drugs:

acetohydroxamic acid (Lithostat);

chloramphenicol;

cimetidine (Tagamet);

etidronate (Didronel);

dimercaprol (an injection used to treat poisoning by arsenic, lead, or mercury);

levodopa (Larodopa, Dopar, Sinemet);

methyldopa (Aldomet); or

penicillamine (Cuprimine).

This list is not complete and there may be other drugs that can interact with ferrous sulfate and folic acid. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

More ferrous sulfate and folic acid resources

Ferrous sulfate and folic acid Drug Interactions
Ferrous sulfate and folic acid Support Group
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Compare ferrous sulfate and folic acid with other medications

Anemia Associated with Iron Deficiency
Iron Deficiency Anemia

Where can I get more information?

Your pharmacist can provide more information about ferrous sulfate and folic acid.

Pain Relief Balm

1. Name Of The Medicinal Product

Pain Relief Balm or PR Heat Rub or Boots Pain Relief Heat Rub

2. Qualitative And Quantitative Composition

Active ingredient
Glycol Monosalicylate	7.5% w/w
Ethyl Nicotinate	1.0% w/w
Nonylic Acid Vanillylamide	0.012% w/w

3. Pharmaceutical Form

Cream

4. Clinical Particulars

4.1 Therapeutic Indications

For the symptomatic relief of muscular pain and stiffness, including simple backache, sciatica, lumbago, fibrositis, rheumatic pain and the muscular aches and joint stiffness following exercise.

4.2 Posology And Method Of Administration

ADULTS AND CHILDREN OVER 12 YEARS:

Apply the cream to the affected area and massage gently until it is absorbed by the skin. Repeat as required.

CHILDREN UNDER 12 YEARS: Not recommended.

For topical use only.

4.3 Contraindications

Hypersensitivity to any of the ingredients. Known hypersensitivity reactions (eg: asthma, rhinitis, urticaria) in response to any other non-steroidal anti-inflammatory drugs (including when taken orally). Not to be applied to broken skin or to come into contact with the eyes or other sensitive parts of the body.

4.4 Special Warnings And Precautions For Use

For external use only.

If symptoms persist, consult your doctor.

Not recommended for children under 12 years.

Caution: Do not apply the cream to broken skin or allow to come into contact with the eyes and other sensitive areas of the body.

Not for use with occlusive dressing.

Wash hands after use.

Keep all medicines out of the reach of children.

4.5 Interaction With Other Medicinal Products And Other Forms Of Interaction

No clinically significant drug interactions known.

4.6 Pregnancy And Lactation

The safety of this product during pregnancy and lactation has not been established but use during these periods is unlikely to constitute a hazard.

4.7 Effects On Ability To Drive And Use Machines

No adverse effects known.

4.8 Undesirable Effects

Occasional hypersensitivity and irritant reactions. May in some individuals give rise to excessive reddening of the skin and feeling of warmth.

4.9 Overdose

Excessive application to the skin may cause excessive reddening and warming . The excess should be removed and the area washed with soap and cold water. Treatment need only be symptomatic. If accidentally ingested, treatment should be symptomatic.

5. Pharmacological Properties

5.1 Pharmacodynamic Properties

Glycol monosalicylate has local analgesic activity by virtue of its counter-irritant and rubefacient properties.

Ethyl nicotinate is a vasodilator with rubefacient properties.

Nonylic acid vanillylamide has rubefacient properties.

5.2 Pharmacokinetic Properties

None stated.

5.3 Preclinical Safety Data

None stated.

6. Pharmaceutical Particulars

6.1 List Of Excipients

Lecithin P Centrolex, propylene glycol, methyl hydroxybenzoate, disodium edetate, cetyl alcohol, silicone fluid F111/20, propyl hydroxybenzoate, purified water, sodium lauryl sulphate, benzyl salicylate.

6.2 Incompatibilities

None stated.

6.3 Shelf Life

18 months.

6.4 Special Precautions For Storage

None.

6.5 Nature And Contents Of Container

A 35g internally lacquered collapsible aluminium tube with latex welt in a cardboard carton.

6.6 Special Precautions For Disposal And Other Handling

None.

7. Marketing Authorisation Holder

The Boots Company PLC

1 Thane Road West

Nottingham NG2 3AA

8. Marketing Authorisation Number(S)

PL 0014/5217R

9. Date Of First Authorisation/Renewal Of The Authorisation

7 November 1984 / 19 September 2001

10. Date Of Revision Of The Text

March 2004

Monday, 27 February 2012

sodium fluoride Oral, Dental, Oromucosal

SOE-dee-um FLOOR-ide

Commonly used brand name(s)

In the U.S.

APF Gel

Aquafresh

CaviRinse

Control Rx

Denta 5000 Plus

Dentagel

Dentall 1100 Plus

EtheDent

Fluorabon

Fluor-A-Day

Fluoridex Daily Defense

Fluoridex Daily Defense Enhanced Whitening

In Canada

Fluorosol

Koala Pals Fluoride Tooth Gel - Berrylicious Flavor

Pedi-Dent

Available Dosage Forms:

Gel/Jelly

Tablet, Chewable

Paste

Solution

Liquid

Tablet, Enteric Coated

Tablet

Lozenge/Troche

Cream

Therapeutic Class: Cariostatic

Uses For sodium fluoride

Fluoride has been found to be helpful in reducing the number of cavities in the teeth. It is usually present naturally in drinking water. However, some areas of the country do not have a high enough level in the water to prevent cavities. To make up for this, extra fluoride may be added to the diet. Some children may require both dietary fluoride and topical fluoride treatments by the dentist. Use of a fluoride toothpaste or rinse may be helpful as well.

Taking extra oral fluoride does not replace good dental habits. These include eating a good diet, brushing and flossing the teeth often, and having regular dental checkups.

Fluoride may also be used for other conditions as determined by your doctor.

sodium fluoride is available only with a prescription.

Importance of Diet

For good health, it is important that you eat a balanced and varied diet. Follow carefully any diet program your health care professional may recommend. For your specific dietary vitamin and/or mineral needs, ask your health care professional for a list of appropriate foods. If you think that you are not getting enough vitamins and/or minerals in your diet, you may choose to take a dietary supplement.

People get needed fluoride from fish, including the bones, tea, and drinking water that has fluoride added to it. Food that is cooked in water containing fluoride or in Teflon-coated pans also provides fluoride. However, foods cooked in aluminum pans provide less fluoride.

The daily amount of fluoride needed is defined in several different ways.

For U.S.—

Recommended Dietary Allowances (RDAs) are the amount of vitamins and minerals needed to provide for adequate nutrition in most healthy persons. RDAs for a given nutrient may vary depending on a person's age, sex, and physical condition (e.g., pregnancy).

Daily Values (DVs) are used on food and dietary supplement labels to indicate the percent of the recommended daily amount of each nutrient that a serving provides. DV replaces the previous designation of United States Recommended Daily Allowances (USRDAs).

For Canada—

Recommended Nutrient Intakes (RNIs) are used to determine the amounts of vitamins, minerals, and protein needed to provide adequate nutrition and lessen the risk of chronic disease.

There is no RDA or RNI for fluoride. Daily recommended intakes for fluoride are generally defined as follows:

Infants and children—

Birth to 3 years of age: 0.1 to 1.5 milligrams (mg).

4 to 6 years of age: 1 to 2.5 mg.

7 to 10 years of age: 1.5 to 2.5 mg.

Adolescents and adults—

1.5 to 4 mg.

Remember:

The total amount of fluoride you get every day includes what you get from the foods and beverages that you eat and what you may take as a supplement.

This total amount should not be greater than the above recommendations, unless ordered by your health care professional. Taking too much fluoride can cause serious problems to the teeth and bones.

Before Using sodium fluoride

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For sodium fluoride, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to sodium fluoride or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Problems in children have not been reported with intake of normal daily recommended amounts. Doses of sodium fluoride that are too large or are taken for a long time may cause bone problems and teeth discoloration in children.

Geriatric

Problems in older adults have not been reported with intake of normal daily recommended amounts. Older people are more likely to have joint pain, kidney problems, or stomach ulcers which may be made worse by taking large doses of sodium fluoride. You should check with your health care professional.

Breast Feeding

Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using sodium fluoride with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use sodium fluoride, or give you special instructions about the use of food, alcohol, or tobacco.

Dairy Food

Proper Use of sodium fluoride

Take sodium fluoride only as directed by your health care professional. Do not take more of it and do not take it more often than ordered. Taking too much fluoride over a period of time may cause unwanted effects.

For individuals taking the chewable tablet form of sodium fluoride:

Tablets should be chewed or crushed before they are swallowed.

sodium fluoride works best if it is taken at bedtime, after the teeth have been thoroughly brushed. Do not eat or drink for at least 15 minutes after taking sodium fluoride.

For individuals taking the oral liquid form of sodium fluoride:

sodium fluoride is to be taken by mouth even though it comes in a dropper bottle. The amount to be taken is to be measured with the specially marked dropper.

Always store sodium fluoride in the original plastic container. Fluoride will affect glass and should not be stored in glass containers.

sodium fluoride may be dropped directly into the mouth or mixed with cereal, fruit juice, or other food. However, if sodium fluoride is mixed with foods or beverages that contain calcium, the amount of sodium fluoride that is absorbed may be reduced.

Dosing

The dose of sodium fluoride will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of sodium fluoride. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage form (lozenges, solution, tablets, or chewable tablets):
- To prevent cavities in the teeth (not enough fluoride in the water):
  - Children—Dose is based on the amount of fluoride in drinking water in your area. Dose is also based on the child's age and must be determined by your health care professional.

Missed Dose

If you miss a dose of sodium fluoride, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using sodium fluoride

The level of fluoride present in the water is different in different parts of the U.S. If you move to another area, check with a health care professional in the new area as soon as possible to see if sodium fluoride is still needed or if the dose needs to be changed. Also, check with your health care professional if you change infant feeding habits (e.g., breast-feeding to infant formula), drinking water (e.g., city water to nonfluoridated bottled water), or filtration (e.g., tap water to filtered tap water).

Do not take calcium supplements or aluminum hydroxide–containing products and sodium fluoride at the same time. It is best to space doses of these two products 2 hours apart, to get the full benefit from each medicine.

Inform your health care professional as soon as possible if you notice white, brown, or black spots on the teeth. These are signs of too much fluoride in children when it is given during periods of tooth development.

sodium fluoride Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

Sodium fluoride in drinking water or taken as a supplement does not usually cause any side effects. However, taking an overdose of fluoride may cause serious problems.

Sores in the mouth and on the lips (rare)

Stop taking sodium fluoride and get emergency help immediately if any of the following effects occur:

Black, tarry stools

bloody vomit

diarrhea

drowsiness

faintness

increased watering of the mouth

nausea or vomiting

shallow breathing

stomach cramps or pain

tremors

unusual excitement

watery eyes

weakness

Check with your doctor as soon as possible if any of the following side effects occur:

Pain and aching of bones

stiffness

white, brown, or black discoloration of the teeth—occurs only during periods of tooth development in children

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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